51 to 60 of 87 Results
Aug 24, 2020 - Kline Lab RNAseq
Artur Matysik; Adeline Yong, 2020, "Related Data for: Adeline Yong RNAseq", https://doi.org/10.21979/N9/1W3HWR, DR-NTU (Data), V1
RAW RNAseq (fastq) files generated by Adeline Yong OG1RF, htrA, srtA, htrAsrtA |
Appointment: Professor Research topics: • Molecular mechanism underlying bacterial pathogenesis and antibiotic resistance • Genomics-guided discovery of microbial natural products |
Jun 18, 2020 - Guillaume THIBAULT
Ho, Nurulain; Yap, Wei Sheng; Xu, Jiaming; Wu, Haoxi; Koh, Jhee Hong; George, Bhawana; Chong, Shu Chen; Taubert, Stefan; Thibault, Guillaume, 2020, "Replication Data for: Stress sensor Ire1 deploys a divergent transcriptional program in response to lipid bilayer stress", https://doi.org/10.21979/N9/5BJD2Z, DR-NTU (Data), V1
Membrane integrity at the endoplasmic reticulum (ER) is tightly regulated, and its disturbance is implicated in metabolic diseases. Using an engineered sensor that activates the unfolded protein response (UPR) exclusively when normal ER membrane lipid composition is compromised,... |
Ludwig, Alexander; Siti Maryam J.M. Yatim; Benedict Tan; Walter Hunziker; Jayantha Gunaratne; Suat Peng, 2020, "The mammalian Crumbs complex defines a distinct polarity domain apical of epithelial tight junctions", https://doi.org/10.21979/N9/TFWJFO, DR-NTU (Data), V2
This dataset contains data pertinent to Tan et al., 2020: The mammalian Crumbs complex defines a distinct polarity domain apical of epithelial tight junctions. |
May 27, 2020 - Guillaume THIBAULT
Beaudoin-Chabot, Caroline; Lei, Wang; Shchepinov, Mikhail S.; Smarun, Alexey V.; Vidović, Drasko; Thibault, Guillaume, 2020, "Related Data for: Deuterated polyunsaturated fatty acids reduce oxidative stress and extend the lifespan of C. elegans", https://doi.org/10.21979/N9/MGPD5H, DR-NTU (Data), V1, UNF:6:vX21yKAg/6svjOec2AP1IA== [fileUNF]
Chemically reinforced essential fatty acids promise to fight numerous age-related diseases including Alzheimer’s, Friedreich’s ataxia and other neurological conditions. The reinforcement is achieved by substituting the atoms of hydrogen at the bis-allylic methylene of these essen... |
May 27, 2020 - Guillaume THIBAULT
Koh, Jhee Hong; Lei, Wang; Beaudoin-Chabot, Caroline; Thibault, Guillaume, 2020, "Replication Data for: Lipid bilayer stress-activated IRE-1 modulates autophagy during endoplasmic reticulum stress", https://doi.org/10.21979/N9/OLY1FU, DR-NTU (Data), V1
Metabolic disorders, such as non-alcoholic fatty liver disease (NAFLD), are emerging as epidemics that affect the global population. One facet of these disorders is attributed to the disturbance of membrane lipid composition. Perturbation of endoplasmic reticulum (ER) homeostasis... |
Appointment: Assistant Professor Research topics: • Molecular Mechanisms of Membrane Compartmentalisation in Cell Polarity • Phase plate imaging and cryo-EM analysis of macromolecular assemblies • What is the tight junction protein ZO3 doing at the base of the primary cilium? |
Apr 3, 2020 - Lin Chun Ling Valerie
Lim, Chew Leng, 2020, "RNA-sequencing data of Balb/c involuting mammary gland treated with anti-Ly6G antibody and estrogen", https://doi.org/10.21979/N9/YBRINN, DR-NTU (Data), V1
Female Balb/c mice were oxvariectomed at lactation day 2, pups forced weaned at lactation day 12 to initiate mammary involution. At 24 hours post-weaning, mice were treated with anti-Ly6G antibodies or isotype control. At 48 hours post-weaning, mice were treated with 20µg/kg of b... |
Appointment: Associate Professor Research topics: • Study of functional differences between progesterone receptor isoform A and and isoform B • Regulation of gene expression and of cell signaling by progesterone • Wnt signaling in breast cancer |
