21 to 30 of 51 Results
Thibault, Guillaume; Yap, Wei Sheng, 2022, "Human PERK rescues unfolded protein response-deficient yeast cells", https://doi.org/10.21979/N9/IGLQOE, DR-NTU (Data), V1
Protein folding and quality control is tightly regulated at the endoplasmic reticulum (ER), and its disruption is associated with many diseases. In eukaryotes, the accumulation of unfolded protein in the ER is sensed by the three sensors, IRE1, PERK, and ATF6 to activate the unfo... |
Jun 11, 2022 - RUEDL Christiane
Nair, Sajith; Wu, Yilun; Nguyen, Trinh Mai; Fink, Katja; Luo, Dahai; Ruedl, Christiane, 2022, "Intranasal Delivery of RIG-I Agonist Drives Pulmonary Myeloid Cell Activation in Mice", https://doi.org/10.21979/N9/XYX2FS, DR-NTU (Data), V1
Viral respiratory infections cause substantial health and economic burden. There is a pressing demand for efficacious vaccination strategies and, therefore, a need for a better understanding of the mechanisms of action of novel potential adjuvants. Here we investigated the effect... |
Hübner, Barbara; von Otter, Eric; Ahsan, Bilal; Wee, Mei Ling; Henriksson, Sara; Ludwig, Alexander; Sandin, Sara, 2022, "Ultrastructure and nuclear architecture of telomeric chromatin revealed by correlative light and electron microscopy", https://doi.org/10.21979/N9/LFBAF8, DR-NTU (Data), V2
This dataset contains data pertinent to Hübner et al., NAR, 2022: Ultrastructure and nuclear architecture of telomeric chromatin revealed by correlative light and electron microscopy. |
Oct 19, 2021 - RUEDL Christiane
Chen, Qi; Nair, Sajith Kumar; Ruedl, Christiane, 2021, "Microbiota regulates the turnover kinetics of intestinal macrophages under steady-state and inflammatory conditions", https://doi.org/10.21979/N9/XBXJPP, DR-NTU (Data), V1
The gut immune system has evolved to co-exist in a mutually beneficial symbiotic relationship with its microflora. Here, using a germ-free fate-mapping mouse model, we provide clear insight into how the enteric commensals determine the kinetics of macrophage turnover. The microbi... |
Oct 6, 2021 - RUEDL Christiane
Wu, Xiaoting; Saito, Takashi; Saido, Takaomi C.; Barron, Anna M; Ruedl, Christiane, 2021, "Microglia and CD206+ border-associated mouse macrophages maintain their embryonic origin during Alzheimer’s disease", https://doi.org/10.21979/N9/9RCHLK, DR-NTU (Data), V1
Brain microglia and border-associated macrophages (BAMs) display distinct spatial, developmental, and phenotypic features. Although at steady-state, the origins of distinct brain macrophages are well-documented, the dynamics of their replenishment in neurodegenerative disorders r... |
Sheriff, Omar, 2021, "Plasmodium falciparum Replication factor C 1 is involved in genotoxic stress response", https://doi.org/10.21979/N9/SRXYUZ, DR-NTU (Data), V1, UNF:6:uq0oSqSaLNW+hDQzSHo//A== [fileUNF]
data related to the article "Plasmodium falciparum Replication factor C 1 is involved in genotoxic stress response" |
Miao, Yansong, 2021, "Replication Data for: Polarisome scaffolder Spa2-mediated macromolecular condensation of Aip5 for actin polymerization", https://doi.org/10.21979/N9/EX7HL5, DR-NTU (Data), V1, UNF:6:OO68jhscRg2tV3QwNHf5Bg== [fileUNF]
published and original data for the publication |
Apr 20, 2021 - Guillaume THIBAULT
Thibault, Guillaume, 2021, "Membrane phospholipid alteration causes chronic ER stress through early degradation of homeostatic ER-resident proteins", https://doi.org/10.21979/N9/OSZXZT, DR-NTU (Data), V1
Phospholipid homeostasis in biological membranes is essential to maintain functions of organelles such as the endoplasmic reticulum. Phospholipid perturbation has been associated to cellular stress responses. However, in most cases, the implication of membrane lipid changes to ho... |
Mar 22, 2021 - RUEDL Christiane
Chen Qi; Lai Simin; Xu Shaohai; Tan Yingrou; Leong Keith; Liu Dehua; Tan Jiachi; Naik Roshan Ratnakar; Barron Anna M; Sunil S. Adav; Chen Jinmiao; Chong Shuzhen; Ng Laiguan; Ruedl Christiane, 2021, "Resident macrophages restrain pathological adipose tissue remodeling and protect vascular integrity in obese mice", https://doi.org/10.21979/N9/9J9BWD, DR-NTU (Data), V1
Tissue-resident macrophages in white adipose tissue (WAT) dynamically adapt to the metabolic changes of their microenvironment that are often induced by excess energy intake. Currently, the exact contribution of these macrophages in obesity-driven WAT remodeling remains controver... |
Nov 13, 2020 - Guillaume THIBAULT
Thibault, Guillaume; Yap, Wei Sheng; Shuy, Peter Jr.; Marvalim, Charlie, 2020, "Replication Data for: The yeast FIT2 homologs are necessary to maintain cellular proteostasis and membrane lipid homeostasis", https://doi.org/10.21979/N9/I7MXVP, DR-NTU (Data), V2
Lipid droplets (LDs) are implicated in conditions of lipid and protein dysregulation. The fat storage inducing transmembrane (FIT) family induces LD formation. Here, we establish a model system to study the role of S. cerevisiae FIT homologues (ScFIT), SCS3 and YFT2, in proteosta... |
