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11 to 20 of 90 Results
AI4Loop Reveals Increased Chromatin Interactions in Cancers that Constitute Therapeutic Vulnerabilities Across 12,000 Samples
Jan 20, 2025 - Fuying DAO
Dao, Fuying; Melissa Jane Fullwood, 2025, "AI4Loop Reveals Increased Chromatin Interactions in Cancers that Constitute Therapeutic Vulnerabilities Across 12,000 Samples", https://doi.org/10.21979/N9/ORBU74, DR-NTU (Data), V1, UNF:6:yu/jmM9lAF6qjIBWiJ1ucw== [fileUNF]
Changes in 3D chromatin interactions may represent actionable vulnerabilities in cancer, yet comprehensive profiling at scale remains technically and financially challenging. Here, we present AI4Loop, a deep learning framework that predicts genome-wide promoter-promoter chromatin...
Fuying DAO(Nanyang Technological University)
Jan 20, 2025
Crystal LING(Nanyang Technological University)
Nov 26, 2024
Reducing microglial lipid load enhances β amyloid phagocytosis in an Alzheimer’s disease mouse model
Sep 30, 2024 - RUEDL Christiane
Ruedl, Christiane; Wu, Xiaoting, 2024, "Reducing microglial lipid load enhances β amyloid phagocytosis in an Alzheimer’s disease mouse model", https://doi.org/10.21979/N9/V4FHSQ, DR-NTU (Data), V1
Macrophages accumulate lipid droplets (LD) under stress and inflammatory conditions. Despite the presence of LD-loaded macrophages in many tissues, including the brain, their contribution to neurodegenerative disorders remains elusive. This study investigated the role of lipid me...
Related data for: Decoding scalp health and microbiome dysbiosis
Sep 25, 2024 - Sreelakshmi CHERUVALLI
Regina, Viduthalai Rasheedkhan; Cheruvalli, Sreelakshmi; Kwok, Weihao; Chopra, Tarun; Rice, Scott, 2024, "Related data for: Decoding scalp health and microbiome dysbiosis", https://doi.org/10.21979/N9/A1SDY5, DR-NTU (Data), V1
Microbial colonization in hair follicles was investigated by direct imaging using scanning electron microscope.
Sreelakshmi CHERUVALLI(Nanyang Technological University)
Sep 25, 2024
Pulsed SILAC-based proteomic analysis unveils hypoxia- and serum starvation-induced de novo protein synthesis with PHD finger protein 14 (PHF14) as a hypoxia sensitive epigenetic regulator in cell cycle progression
Jul 24, 2024 - Newman SZE Siu Kwan
Sze, Siu Kwan, 2024, "Pulsed SILAC-based proteomic analysis unveils hypoxia- and serum starvation-induced de novo protein synthesis with PHD finger protein 14 (PHF14) as a hypoxia sensitive epigenetic regulator in cell cycle progression", https://doi.org/10.21979/N9/R0DSBP, DR-NTU (Data), V1
Hypoxia is an environmental cue that is associated with multiple tumorigenic processes such as immunosuppression, angiogenesis, cancer invasion, metastasis, drug resistance, and poor clinical outcomes. When facing hypoxic stress, cells initiate several adaptive responses such as...
Newman SZE Siu Kwan(Nanyang Technological University)
Jul 24, 2024
Research topics: • Proteomics • Biomedical research • Translational research
TAN Suet Mien(Nanyang Technological University)
TAN Suet Mien logo
Jul 15, 2024
Research topics: Confocal images work files on kindlin-2 mutants localization in cells
Data for Project: Heterologous Production Of Cannabinoids In Proprietary Streptomyces Hosts
Jul 9, 2024 - NRF Project Grant SBP01
Liang, Zhao-Xun, 2024, "Data for Project: Heterologous Production Of Cannabinoids In Proprietary Streptomyces Hosts", https://doi.org/10.21979/N9/I4TNKA, DR-NTU (Data), V1
Enclosed here are genome sequencing data for the two microbial chassis, protocols, methods, and other chemical and biochemical data.
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