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AI4Loop Reveals Increased Chromatin Interactions in Cancers that Constitute Therapeutic Vulnerabilities Across 12,000 Samples
Jan 20, 2025
Dao, Fuying; Melissa Jane Fullwood, 2025, "AI4Loop Reveals Increased Chromatin Interactions in Cancers that Constitute Therapeutic Vulnerabilities Across 12,000 Samples", https://doi.org/10.21979/N9/ORBU74, DR-NTU (Data), V1, UNF:6:yu/jmM9lAF6qjIBWiJ1ucw== [fileUNF]
Changes in 3D chromatin interactions may represent actionable vulnerabilities in cancer, yet comprehensive profiling at scale remains technically and financially challenging. Here, we present AI4Loop, a deep learning framework that predicts genome-wide promoter-promoter chromatin...
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