Francesc Xavier Roca Castella

Appointment: Associate Professor, School of Biological Sciences
Assistant Chair (Lifelong Learning), School of Biological Sciences (SBS)

Research topics:
• focus on the study of the mechanisms of pre-messenger RNA splicing in human cells
• identify new therapeutic targets, and/or to develop RNA-based therapies for human diseases

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1 to 5 of 5 Results

PD-L1 alternative splicing Dec 6, 2023 - PD-L1 alternative splicing XR Roca Castella, Francesc Xavier, 2023, "PD-L1 alternative splicing", https://doi.org/10.21979/N9/MICQRU, DR-NTU (Data), V1 PhD thesis of Dr Yashu Zhen, graduated in 2022. All data in thesis pertains to this project. Publication being put together with these data and new experiments being finished.
PD-L1 alternative splicing XR(Nanyang Technological University) Dec 6, 2023
Excel file with DASEs for Lorenzini et al (Roca) RNA 2019 May 27, 2019 - Supporting data for Lorenzini et al RNA 2019 Roca Castella, Francesc Xavier, 2019, "Excel file with DASEs for Lorenzini et al (Roca) RNA 2019", https://doi.org/10.21979/N9/3RYIVP, DR-NTU (Data), V1, UNF:6:fIX5Bo5JAZnoC+WXEh4DBQ== [fileUNF] 7 RNA-seq samples for K562 cells, PRPF40B knockout and rescue with WT or MDS mutant PRPF40B. Excel file with Differential Alternative Splicing Events (DASEs) from RNA-seq data using rMATS.. Only events that pass the cutoffs.
Excel file with DEGs for Lorenzini et al (Roca) RNA 2019 May 27, 2019 - Supporting data for Lorenzini et al RNA 2019 Roca Castella, Francesc Xavier, 2019, "Excel file with DEGs for Lorenzini et al (Roca) RNA 2019", https://doi.org/10.21979/N9/MUULD6, DR-NTU (Data), V1, UNF:6:s7n2Wk81UQPaJyi6yrLKdg== [fileUNF] DEGs and other gene expression data from RNA-seq data. 7 RNA-seq samples for K562 cells, PRPF40B knockout and rescue with WT or MDS mutant PRPF40B. Excel file with all the Differentially Expressed Genes (DEGs). Significant DEGs labeled 'Yes', others 'No'.
Supporting data for Lorenzini et al RNA 2019(Nanyang Technological University) May 27, 2019 Supporting data for RNA paper 2019, Lorenzini et al (corresponding author Roca). 7 RNA-seq samples for K562 cells, PRPF40B knockout and rescue with WT or MDS mutant PRPF40B. Excel file with all the Differentially Expressed Genes (DEGs). Significant DEGs labeled 'Yes', others 'No'...

PD-L1 alternative splicing

Dec 6, 2023 - PD-L1 alternative splicing XR

Roca Castella, Francesc Xavier, 2023, "PD-L1 alternative splicing", https://doi.org/10.21979/N9/MICQRU, DR-NTU (Data), V1

PhD thesis of Dr Yashu Zhen, graduated in 2022. All data in thesis pertains to this project. Publication being put together with these data and new experiments being finished.

PD-L1 alternative splicing XR(Nanyang Technological University)

Dec 6, 2023

Excel file with DASEs for Lorenzini et al (Roca) RNA 2019

May 27, 2019 - Supporting data for Lorenzini et al RNA 2019

Roca Castella, Francesc Xavier, 2019, "Excel file with DASEs for Lorenzini et al (Roca) RNA 2019", https://doi.org/10.21979/N9/3RYIVP, DR-NTU (Data), V1, UNF:6:fIX5Bo5JAZnoC+WXEh4DBQ== [fileUNF]

7 RNA-seq samples for K562 cells, PRPF40B knockout and rescue with WT or MDS mutant PRPF40B. Excel file with Differential Alternative Splicing Events (DASEs) from RNA-seq data using rMATS.. Only events that pass the cutoffs.

Excel file with DEGs for Lorenzini et al (Roca) RNA 2019

May 27, 2019 - Supporting data for Lorenzini et al RNA 2019

Roca Castella, Francesc Xavier, 2019, "Excel file with DEGs for Lorenzini et al (Roca) RNA 2019", https://doi.org/10.21979/N9/MUULD6, DR-NTU (Data), V1, UNF:6:s7n2Wk81UQPaJyi6yrLKdg== [fileUNF]

DEGs and other gene expression data from RNA-seq data. 7 RNA-seq samples for K562 cells, PRPF40B knockout and rescue with WT or MDS mutant PRPF40B. Excel file with all the Differentially Expressed Genes (DEGs). Significant DEGs labeled 'Yes', others 'No'.

Supporting data for Lorenzini et al RNA 2019(Nanyang Technological University)

May 27, 2019

Supporting data for RNA paper 2019, Lorenzini et al (corresponding author Roca). 7 RNA-seq samples for K562 cells, PRPF40B knockout and rescue with WT or MDS mutant PRPF40B. Excel file with all the Differentially Expressed Genes (DEGs). Significant DEGs labeled 'Yes', others 'No'...

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