Appointment: Associate Professor

Research topics:

• Lipid Regulations in Eukaryotes

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Apr 20, 2021
Thibault, Guillaume, 2021, "Membrane phospholipid alteration causes chronic ER stress through early degradation of homeostatic ER-resident proteins", https://doi.org/10.21979/N9/OSZXZT, DR-NTU (Data), V1
Phospholipid homeostasis in biological membranes is essential to maintain functions of organelles such as the endoplasmic reticulum. Phospholipid perturbation has been associated to cellular stress responses. However, in most cases, the implication of membrane lipid changes to ho...
Nov 13, 2020
Thibault, Guillaume; Yap, Wei Sheng; Shuy, Peter Jr.; Marvalim, Charlie, 2020, "Replication Data for: The yeast FIT2 homologs are necessary to maintain cellular proteostasis and membrane lipid homeostasis", https://doi.org/10.21979/N9/I7MXVP, DR-NTU (Data), V2
Lipid droplets (LDs) are implicated in conditions of lipid and protein dysregulation. The fat storage inducing transmembrane (FIT) family induces LD formation. Here, we establish a model system to study the role of S. cerevisiae FIT homologues (ScFIT), SCS3 and YFT2, in proteosta...
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