Appointment: Associate Vice President (Biomedical and Life Sciences), Nanyang Technological University
Professor, School of Biological Sciences

Research topics:

His research interests focus on the molecular mechanisms by which the malaria parasite is able to avoid host immunity and adapt to changes in the host cell environment. One of the main problems in developing an efficient malaria vaccine is the ability of the parasite to evade host immune responses. Immune evasion happens both at the level of the infected red blood cell and at the process of invasion, the step at which the parasite infects a new cell.

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Sep 20, 2019 - Comparative transcriptome
Hoo, Regina May Ling, 2019, "Transcriptome profiling reveals functional variation in Plasmodium falciparum parasites from controlled human malaria infection studies", https://doi.org/10.21979/N9/VKPDCD, DR-NTU (Data), V1, UNF:6:gWhTU82zoCivH8NbdrP3/Q== [fileUNF]
Background The transcriptome of Plasmodium falciparum clinical isolates varies according to strain, mosquito bites, disease severity and clinical history. Therefore, it remains a challenge to directly interpret the parasite's transcriptomic information into a more general biologi...
Jul 8, 2019 - Comparative transcriptome
Hoo, Regina May Ling, 2019, "Integrated Analysis of the Plasmodium Species Transcriptome", https://doi.org/10.21979/N9/UBCFAP, DR-NTU (Data), V1, UNF:6:1IVTRLN2QZa2dxWQtdfWVw== [fileUNF]
The genome sequence available for different Plasmodium species is a valuable resource for understanding malaria parasite biology. However, comparative genomics on its own cannot fully explain all the species-specific differences which suggests that other genomic aspects such as r...
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