RUEDL Christiane

Appointment: Associate Chair (Research), School of Biological Sciences
Professor, School of Biological Sciences

Research topics:

• Immunology
• Macrophages
• Cancer Immunology

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1 to 10 of 77 Results

Reducing microglial lipid load enhances β amyloid phagocytosis in an Alzheimer’s disease mouse model Sep 30, 2024 Ruedl, Christiane; Wu, Xiaoting, 2024, "Reducing microglial lipid load enhances β amyloid phagocytosis in an Alzheimer’s disease mouse model", https://doi.org/10.21979/N9/V4FHSQ, DR-NTU (Data), V1 Macrophages accumulate lipid droplets (LD) under stress and inflammatory conditions. Despite the presence of LD-loaded macrophages in many tissues, including the brain, their contribution to neurodegenerative disorders remains elusive. This study investigated the role of lipid me...
Figure _6-2.7z Sep 30, 2024 - Reducing microglial lipid load enhances β amyloid phagocytosis in an Alzheimer’s disease mouse model 7Z Archive - 390.1 MB - MD5: 92acb47dfe45cff8b9948fdf2be9f9b0
Figure 7_2.7z Sep 30, 2024 - Reducing microglial lipid load enhances β amyloid phagocytosis in an Alzheimer’s disease mouse model 7Z Archive - 1.6 GB - MD5: a8dfb4c9066b3e0be5174cebd23263fe
Supplementary Figure S9_2.7z Sep 30, 2024 - Reducing microglial lipid load enhances β amyloid phagocytosis in an Alzheimer’s disease mouse model 7Z Archive - 904.2 MB - MD5: 9101a7ee417b1f7c9f2785f996240917
Lipidomic analysis.csv Sep 30, 2024 - Reducing microglial lipid load enhances β amyloid phagocytosis in an Alzheimer’s disease mouse model Comma Separated Values - 39.3 KB - MD5: 89efe74e3095fc467dbf784d283dcc4a
Turnover kinetics of pancreatic macrophages in lean and obese diabetic mice Jan 20, 2024 Ruedl, Christiane; Ma, Ziyuan, 2022, "Turnover kinetics of pancreatic macrophages in lean and obese diabetic mice", https://doi.org/10.21979/N9/2YJP6X, DR-NTU (Data), V2 Pancreatic resident macrophages, a heterogeneous family of cells with distinct origins and phenotypes, are the main myeloid cells in exocrine and endocrine tissues. Adult exocrine F4/80hi macrophages consist of three different subsets based on the embryonic marker Tim-4 and MHC I...
ZM Thesis 3.1.zip Jan 20, 2024 - Turnover kinetics of pancreatic macrophages in lean and obese diabetic mice ZIP Archive - 309.5 KB - MD5: 1a9c154273c5fae992387100c5828cdd Thesis result section 3.1 data
ZM Thesis 3.2.1.zip Jan 20, 2024 - Turnover kinetics of pancreatic macrophages in lean and obese diabetic mice ZIP Archive - 4.1 GB - MD5: ac7c8623ee92545530d1f2b40ecbe213 Thesis result section 3.2.1 aging
ZM Thesis 3.2.2-3.2.3.zip Jan 20, 2024 - Turnover kinetics of pancreatic macrophages in lean and obese diabetic mice ZIP Archive - 3.6 GB - MD5: d0299105d307e09e0b39fcd28d16e83e Thesis result section 3.2.2-3.2.3
ZM Thesis 3.2.zip Jan 20, 2024 - Turnover kinetics of pancreatic macrophages in lean and obese diabetic mice ZIP Archive - 359.5 MB - MD5: 902060359cdf6bcee68a9a7dcd8bbde3 Thesis result section 3.2 gating strategy

Reducing microglial lipid load enhances β amyloid phagocytosis in an Alzheimer’s disease mouse model

Sep 30, 2024

Ruedl, Christiane; Wu, Xiaoting, 2024, "Reducing microglial lipid load enhances β amyloid phagocytosis in an Alzheimer’s disease mouse model", https://doi.org/10.21979/N9/V4FHSQ, DR-NTU (Data), V1

Macrophages accumulate lipid droplets (LD) under stress and inflammatory conditions. Despite the presence of LD-loaded macrophages in many tissues, including the brain, their contribution to neurodegenerative disorders remains elusive. This study investigated the role of lipid me...

Figure _6-2.7z

Sep 30, 2024 - Reducing microglial lipid load enhances β amyloid phagocytosis in an Alzheimer’s disease mouse model

7Z Archive - 390.1 MB -

Figure 7_2.7z

Sep 30, 2024 - Reducing microglial lipid load enhances β amyloid phagocytosis in an Alzheimer’s disease mouse model

7Z Archive - 1.6 GB -

Supplementary Figure S9_2.7z

Sep 30, 2024 - Reducing microglial lipid load enhances β amyloid phagocytosis in an Alzheimer’s disease mouse model

7Z Archive - 904.2 MB -

Lipidomic analysis.csv

Sep 30, 2024 - Reducing microglial lipid load enhances β amyloid phagocytosis in an Alzheimer’s disease mouse model

Comma Separated Values - 39.3 KB -

Turnover kinetics of pancreatic macrophages in lean and obese diabetic mice

Jan 20, 2024

Ruedl, Christiane; Ma, Ziyuan, 2022, "Turnover kinetics of pancreatic macrophages in lean and obese diabetic mice", https://doi.org/10.21979/N9/2YJP6X, DR-NTU (Data), V2

Pancreatic resident macrophages, a heterogeneous family of cells with distinct origins and phenotypes, are the main myeloid cells in exocrine and endocrine tissues. Adult exocrine F4/80hi macrophages consist of three different subsets based on the embryonic marker Tim-4 and MHC I...

ZM Thesis 3.1.zip

Jan 20, 2024 - Turnover kinetics of pancreatic macrophages in lean and obese diabetic mice

ZIP Archive - 309.5 KB -

Thesis result section 3.1 data

ZM Thesis 3.2.1.zip

Jan 20, 2024 - Turnover kinetics of pancreatic macrophages in lean and obese diabetic mice

ZIP Archive - 4.1 GB -

Thesis result section 3.2.1 aging

ZM Thesis 3.2.2-3.2.3.zip

Jan 20, 2024 - Turnover kinetics of pancreatic macrophages in lean and obese diabetic mice

ZIP Archive - 3.6 GB -

Thesis result section 3.2.2-3.2.3

ZM Thesis 3.2.zip

Jan 20, 2024 - Turnover kinetics of pancreatic macrophages in lean and obese diabetic mice

ZIP Archive - 359.5 MB -

Thesis result section 3.2 gating strategy

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