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1 to 7 of 7 Results
Aug 19, 2019
Ivan, Fransiskus Xaverius, 2019, "Virulence Information for Influenza Virus Infection (VI2VI) in Mice", https://doi.org/10.21979/N9/ILQBAB, DR-NTU (Data), V2, UNF:6:tcVfZQlYB60+SEUz7/g4jQ== [fileUNF]
Datasets for Virulence Information for Influenza Virus Infection (VI2VI) in Mice. Please see VI2VI-creation.docx for further details. The analyses of the datasets was first provided as a bioRxiv preprint (see Related Publication) and it has now been accepted for BMC Supplements d...
Apr 26, 2019
Ivan, Fransiskus Xaverius; Akhila Deshpande; Chun, Wei Lim; Kwoh, Chee Keong, 2019, "Phylogenetic Tree-based Pipeline for Uncovering Mutational Patterns during Influenza Virus Evolution", https://doi.org/10.21979/N9/PDYCUD, DR-NTU (Data), V1
Various computational and statistical approaches have been proposed to uncover the mutational patterns of rapidly evolving influenza viral genes. A problem that draws much attention is to identify pairs of sites that potentially co-mutate to contribute to the overall fitness of t...
Apr 22, 2019
Yin, Rui, 2019, "Computational identification of physicochemical signatures for host tropism of influenza A virus", https://doi.org/10.21979/N9/5RIS7R, DR-NTU (Data), V1
Avian influenza viruses from migratory birds have managed to cross host species barriers and infected various hosts like human and swine. Epidemics and pandemics might occur when influenza viruses are adapted to humans, causing deaths and enormous economic loss. Receptor-binding...
Apr 22, 2019
Yin, Rui, 2019, "Influenza H1N1 antigenic and sequence data", https://doi.org/10.21979/N9/O5XL2X, DR-NTU (Data), V1
H1N1 is the earliest emerging subtype of influenza A viruses with available genomic sequences, has caused several pandemics and seasonal epidemics, resulting in millions of deaths and enormous economic losses. Timely determination of new antigenic variants is crucial for the vacc...
Apr 3, 2019
Zhou, Xinrui, 2019, "Code and data for CFreeEnS", https://doi.org/10.21979/N9/4YDZED, DR-NTU (Data), V1
A method called Context-Free Encoding Scheme (CFreeEnS) was proposed to encode protein sequence pairs into a numeric matrix. CFreeEnS takes advantage of rich information about the physiochemical and structural properties of amino acids. This encoding scheme keeps information abou...
Mar 22, 2019
Zhou, Xinrui; Zheng, Jie; Ivan, Fransiskus Xaverius; Yin, Rui; Shoba Ranganathan; Chow, Vincent T. K.; Kwoh, Chee-Keong, 2019, "Additional files for: Computational analysis of the receptor binding specificity of novel influenza A/H7N9 viruses.", https://doi.org/10.21979/N9/TQEOP6, DR-NTU (Data), V1
BACKGROUND: Influenza viruses are undergoing continuous and rapid evolution. The fatal influenza A/H7N9 has drawn attention since the first wave of infections in March 2013 and raised more grave concerns with its increased potential to spread among humans. Experimental studies ha...
Mar 22, 2019
Chen, Haifen; Zhou, Xinrui; Zheng, Jie; Kwoh, Chee Keong, 2019, "Supplementary materials and Matlab code for "Rules of co-occurring mutations characterize the antigenic evolution of human influenza A/H3N2, A/H1N1 and B viruses"", https://doi.org/10.21979/N9/H73L8Y, DR-NTU (Data), V1
Background The human influenza viruses undergo rapid evolution (especially in hemagglutinin (HA), a glycoprotein on the surface of the virus), which enables the virus population to constantly evade the human immune system. Therefore, the vaccine has to be updated every year to st...
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