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10,231 to 10,240 of 10,282 Results
Dec 18, 2018 - Su I-Hsin
Venkatesan, Nandini; Wong, Jong Fu; Tan, Kuan Pern; Chung, Hwa Hwa; Yau, Yin Hoe; Cukuroglu, Egin; Allahverdi, Abdollah; Nordenskiold, Lars; Göke, Jonathan; Shochat, Susana Geifman; Lin, Valerie Chun Ling; Madhusudhan, M.S.; Su, I-Hsin, 2018, "Related Data for: EZH2 promotes neoplastic transformation through VAV interaction-dependent extranuclear mechanisms", https://doi.org/10.21979/N9/AJYMP5, DR-NTU (Data), V1, UNF:6:Jip7WN9yR3MzhAn3KTokSQ== [fileUNF]
This dataset contains RNA-seq data and supplementary data relating to the journal article "EZH2 promotes neoplastic transformation through VAV interaction-dependent extranuclear mechanisms" which was published in Ocogene on 25 Jan 2018.
AVI Video - 6.2 MB - MD5: a3a4922fd3570459139471192c4fb490
Data
Supplementary Video S1 (related to Figure 4) EZH2ΔNLS promotes adhesion turnover. The turnover of adhesion structures in EZH2 knockdown H16N2 cells overexpressing EZH2ΔNLS and mCherry-Paxillin was monitored by mCherry signals in time-lapse imaging.
AVI Video - 7.4 MB - MD5: 06ecc4f6d3e874c24e5fb52c51e21bbd
Data
Supplementary Video 2 (related to Figure 4) VAV interaction mutant EZH2 prevents adhesion turnover. The turnover of adhesion structures in EZH2 knockdown H16N2 cells overexpressing VAV interaction mutant EZH2 (EZH2-VAV/MT) and mCherry-Paxillin was monitored by mCherry signals...
AVI Video - 7.4 MB - MD5: fbcfb998aacce8ac2bd35035119d9d08
Data
Supplementary video 3 (related to Figure 5) Un-methylatable Talin1 contributes to extremely stable adhesion structures (Talin1-K2454Q). The turnover of adhesion structures in unmethylatable GFP-Talin1 (Talin1-K2454Q) overexpressing H16N2 cells was monitored by GFP signals in t...
AVI Video - 7.4 MB - MD5: 13a7ed94429fb9bc1120eb3dbb8817c6
Data
Supplementary video 4 (related to Figure 5). Methyl-mimicking Talin1 promotes adhesion turnover. The turnover of adhesion structures in methyl-mimicking GFP-Talin1 (Talin1-K2454F) overexpressing H16N2 cells was monitored by GFP signals in time-lapse live imaging.
MPEG-4 Video - 3.1 MB - MD5: 9834879235ecf0907ff4af79f80b11f0
Data
Supplementary video 5 (related to Figure 8) 3D reconstruction of Z-stack confocal images of EZH2 expression in breast cancer stem cells (CD44hiSP). Sorted CD44hi Rhodamine 123low side population (SP) MDA-MB-231 cells were stained with anti-EZH2 specific antibody (green) and DA...
MPEG-4 Video - 2.8 MB - MD5: e7dfb4b06af4f207afa98665cab199d6
Data
Supplementary video 6 (related to Figure 8) 3D reconstruction of Z-stack confocal images of EZH2 expression in breast cancer cells (CD44low). Sorted CD44low Rhodamine 123hi MDA-MB-231 cells were stained with anti-EZH2 specific antibody (green) and DAPI (blue) for nuclei.
Tabular Data - 185 B - 4 Variables, 5 Observations - UNF:6:Jip7WN9yR3MzhAn3KTokSQ==
Data
Source data for main figures in combined excel file
Adobe PDF - 5.6 MB - MD5: d68f60f31416e4eb1b3b4166d0628b94
Documentation
Legends for the supplementary data and files
Dec 20, 2017 - RUEDL Christiane
Soncin, Irene; Sheng, Jianpeng; Chen, Qi; Foo, Shihui; Duan, Kaibo; Lum, Josephine; Poidinger, Michael; Zolezzi, Francesca; Karjalainen, Klaus; Ruedl, Christiane, 2017, "Replication Data for: The tumour microenvironment creates a niche for the self-renewal of tumour-promoting macrophages in colon adenoma.", https://doi.org/10.21979/N9/EQXCRF, DR-NTU (Data), V1
Circulating CCR2+ monocytes are crucial for maintaining the adult tissue-resident F4/80hiMHCIIhi macrophage pool in the intestinal lamina propria. Here we show that, a subpopulation of CCR2-independent F4/80hiMHCIIlow macrophages, which are the most abundant F4/80hi cells in neon...
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