41 to 50 of 92 Results
Thibault, Guillaume; Beaudoin-Chabot, Caroline; Wang, Lei; Celik, Cenk; Khalid, Aishah Abdul; Thalappilly, Subhash; Koh, Jhee Hong; Xu, Shiyi; Lim, Venus Wen Xuan; Low, Ann Don, 2022, "Replication Data for: The unfolded protein response reverses the effects of glucose on lifespan in chemically-sterilized C. elegans", https://doi.org/10.21979/N9/GEPEAG, DR-NTU (Data), V1, UNF:6:bDcV8UXFkGMeff3EFRkBYA== [fileUNF]
Metabolic diseases often share common traits, including accumulation of unfolded proteins in the endoplasmic reticulum (ER). Upon ER stress, the unfolded protein response (UPR) is activated to limit cellular damage which weakens with age. Here, we show that Caenorhabditis elegans... |
Thibault, Guillaume; Yap, Wei Sheng, 2022, "Human PERK rescues unfolded protein response-deficient yeast cells", https://doi.org/10.21979/N9/IGLQOE, DR-NTU (Data), V1
Protein folding and quality control is tightly regulated at the endoplasmic reticulum (ER), and its disruption is associated with many diseases. In eukaryotes, the accumulation of unfolded protein in the ER is sensed by the three sensors, IRE1, PERK, and ATF6 to activate the unfo... |
Jun 11, 2022 - RUEDL Christiane
Nair, Sajith; Wu, Yilun; Nguyen, Trinh Mai; Fink, Katja; Luo, Dahai; Ruedl, Christiane, 2022, "Intranasal Delivery of RIG-I Agonist Drives Pulmonary Myeloid Cell Activation in Mice", https://doi.org/10.21979/N9/XYX2FS, DR-NTU (Data), V1
Viral respiratory infections cause substantial health and economic burden. There is a pressing demand for efficacious vaccination strategies and, therefore, a need for a better understanding of the mechanisms of action of novel potential adjuvants. Here we investigated the effect... |
Hübner, Barbara; Von Otter, Eric; Ahsan, Bilal; Wee, Mei Ling; Henriksson, Sara; Ludwig, Alexander; Sandin, Sara, 2022, "Ultrastructure and nuclear architecture of telomeric chromatin revealed by correlative light and electron microscopy", https://doi.org/10.21979/N9/LFBAF8, DR-NTU (Data), V2
This dataset contains data pertinent to Hübner et al., NAR, 2022: Ultrastructure and nuclear architecture of telomeric chromatin revealed by correlative light and electron microscopy. |
Oct 19, 2021 - RUEDL Christiane
Chen, Qi; Nair, Sajith Kumar; Ruedl, Christiane, 2021, "Microbiota regulates the turnover kinetics of intestinal macrophages under steady-state and inflammatory conditions", https://doi.org/10.21979/N9/XBXJPP, DR-NTU (Data), V1
The gut immune system has evolved to co-exist in a mutually beneficial symbiotic relationship with its microflora. Here, using a germ-free fate-mapping mouse model, we provide clear insight into how the enteric commensals determine the kinetics of macrophage turnover. The microbi... |
Oct 6, 2021 - RUEDL Christiane
Wu, Xiaoting; Saito, Takashi; Saido, Takaomi C.; Barron, Anna M; Ruedl, Christiane, 2021, "Microglia and CD206+ border-associated mouse macrophages maintain their embryonic origin during Alzheimer’s disease", https://doi.org/10.21979/N9/9RCHLK, DR-NTU (Data), V1
Brain microglia and border-associated macrophages (BAMs) display distinct spatial, developmental, and phenotypic features. Although at steady-state, the origins of distinct brain macrophages are well-documented, the dynamics of their replenishment in neurodegenerative disorders r... |
Sheriff, Omar, 2021, "Plasmodium falciparum Replication factor C 1 is involved in genotoxic stress response", https://doi.org/10.21979/N9/SRXYUZ, DR-NTU (Data), V1, UNF:6:uq0oSqSaLNW+hDQzSHo//A== [fileUNF]
data related to the article "Plasmodium falciparum Replication factor C 1 is involved in genotoxic stress response" |
Jul 28, 2021
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Miao, Yansong, 2021, "Replication Data for: Polarisome scaffolder Spa2-mediated macromolecular condensation of Aip5 for actin polymerization", https://doi.org/10.21979/N9/EX7HL5, DR-NTU (Data), V1, UNF:6:OO68jhscRg2tV3QwNHf5Bg== [fileUNF]
published and original data for the publication |
Research topics: He is interested in how eukaryotic cells dynamically reorganize their actin cytoskeletons to power endocytosis, polarized delivery of vesicles for cell growth, cell movement, and cell division. |
