Alexander LUDWIG

Research topics:
• Molecular Mechanisms of Membrane Compartmentalisation in Cell Polarity
• Phase plate imaging and cryo-EM analysis of macromolecular assemblies
• What is the tight junction protein ZO3 doing at the base of the primary cilium?

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1 to 10 of 1,089 Results

FIB-SEM_Raw.tif Aug 10, 2026 - Related data for: Bulk delivery of a preassembled apical surface initiates epithelial lumen formation TIFF Image - 4.7 GB - MD5: 9beb0466d515e8435323b29f058afb90 Raw FIB-SEM data of an MDCK PAP stage (related to Figure 6A-C and Supplemental Figure S10)
PPI network.cys Aug 10, 2026 - Related data for: Bulk delivery of a preassembled apical surface initiates epithelial lumen formation Unknown - 2.0 MB - MD5: 9395385ee26fd8e6c62101d56bbe0487 Cytoscape file of a time-resolved PPI network of PALS1-APEX2-EGFP in a calcium switch assay (related to Figure 3 and Supplemental Figure S5)
Supplementary File S1.tab Aug 10, 2026 - Related data for: Bulk delivery of a preassembled apical surface initiates epithelial lumen formation Tabular Data - 68.5 KB - 22 Variables, 278 Observations - UNF:6:7xutXEs/YgZRTaQMxjKFCw== Time-resolved proximity proteomics data of Pals1-APEX2-EGFP in a calcium switch assay
Ghosh Nature Comm Figures Folder.zip Aug 10, 2026 - Related data for: Bulk delivery of a preassembled apical surface initiates epithelial lumen formation ZIP Archive - 3.5 GB - MD5: 8fd258ee9df437b08e1c25a2f5e50084 All Main and Supplemental Figures packaged as Indesign Folder. All primary data shown in the figures are contained within this folder. High resolution PDFs are also included in the package.
SEM Analysis.zip Aug 10, 2026 - Related data for: Bulk delivery of a preassembled apical surface initiates epithelial lumen formation ZIP Archive - 66.1 MB - MD5: 2a08c56cff67df049dbae8e4747e1684 SEM Raw data (related to Figure 7 and Supplemental Figure S13)
Dataset S1.tab Jul 17, 2026 - Related data for: Homer condensates orchestrate YAP-Wnt signaling crosstalk downstream of the Crumbs polarity complex Tabular Data - 491.2 KB - 33 Variables, 871 Observations - UNF:6:49ryGEUSiGuXOIikQSttwQ== RNA sequencing data of Homer triple KO MDCK cells
RNASeq Data top100 DEGs.png Jul 17, 2026 - Related data for: Homer condensates orchestrate YAP-Wnt signaling crosstalk downstream of the Crumbs polarity complex PNG Image - 367.2 KB - MD5: 52f4d8da12d7d28d2ecc14f682d0a092 Heatmap showing the top 100 differentially expressed genes in Homer triple KO MDCK cells. Related to Dataset S1 and Supplemental Figure S4A.
Yatim PNAS 2026 Figures Folder.zip Jul 17, 2026 - Related data for: Homer condensates orchestrate YAP-Wnt signaling crosstalk downstream of the Crumbs polarity complex ZIP Archive - 702.2 MB - MD5: 3b2d5af61005602958c667f5133e996a All Main and Supplemental Figures of Yatim et al 2026 packaged as an Indesign Document. Primary data is included in the package
Yatim Source data.zip Jul 17, 2026 - Related data for: Homer condensates orchestrate YAP-Wnt signaling crosstalk downstream of the Crumbs polarity complex ZIP Archive - 106.7 MB - MD5: ba9ec985c8d5b6ad10bff44fd3b23795 Yatim et al Source Data. qPCR, TEAD and TCF/LEF luciferase reporter assays, RNA sequencing analysis, FRAP, YAP/pYAP Western blots, ...
map-data-2024.10.25-16.45.53.578.jpk-force-map-2.zip Apr 21, 2025 - Related data for: Acute chromatin decompaction stiffens the nucleus as revealed by nanopillar-induced nuclear deformation in cells ZIP Archive - 2.6 MB - MD5: 2ac47da93246621011522d4b2e98e804

FIB-SEM_Raw.tif

Aug 10, 2026 - Related data for: Bulk delivery of a preassembled apical surface initiates epithelial lumen formation

TIFF Image - 4.7 GB -

Raw FIB-SEM data of an MDCK PAP stage (related to Figure 6A-C and Supplemental Figure S10)

PPI network.cys

Aug 10, 2026 - Related data for: Bulk delivery of a preassembled apical surface initiates epithelial lumen formation

Unknown - 2.0 MB -

Cytoscape file of a time-resolved PPI network of PALS1-APEX2-EGFP in a calcium switch assay (related to Figure 3 and Supplemental Figure S5)

Supplementary File S1.tab

Aug 10, 2026 - Related data for: Bulk delivery of a preassembled apical surface initiates epithelial lumen formation

Tabular Data - 68.5 KB - 22 Variables, 278 Observations -

Time-resolved proximity proteomics data of Pals1-APEX2-EGFP in a calcium switch assay

Ghosh Nature Comm Figures Folder.zip

Aug 10, 2026 - Related data for: Bulk delivery of a preassembled apical surface initiates epithelial lumen formation

ZIP Archive - 3.5 GB -

All Main and Supplemental Figures packaged as Indesign Folder. All primary data shown in the figures are contained within this folder. High resolution PDFs are also included in the package.

SEM Analysis.zip

Aug 10, 2026 - Related data for: Bulk delivery of a preassembled apical surface initiates epithelial lumen formation

ZIP Archive - 66.1 MB -

SEM Raw data (related to Figure 7 and Supplemental Figure S13)

Dataset S1.tab

Jul 17, 2026 - Related data for: Homer condensates orchestrate YAP-Wnt signaling crosstalk downstream of the Crumbs polarity complex

Tabular Data - 491.2 KB - 33 Variables, 871 Observations -

RNA sequencing data of Homer triple KO MDCK cells

RNASeq Data top100 DEGs.png

Jul 17, 2026 - Related data for: Homer condensates orchestrate YAP-Wnt signaling crosstalk downstream of the Crumbs polarity complex

PNG Image - 367.2 KB -

Heatmap showing the top 100 differentially expressed genes in Homer triple KO MDCK cells. Related to Dataset S1 and Supplemental Figure S4A.