SynLethDB: synthetic lethality database towards discovery of selective and sensitive anticancer drug targets (doi:10.21979/N9/CVEVDZ)

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Part 2: Study Description
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Document Description

Citation

Title:

SynLethDB: synthetic lethality database towards discovery of selective and sensitive anticancer drug targets

Identification Number:

doi:10.21979/N9/CVEVDZ

Distributor:

DR-NTU (Data)

Date of Distribution:

2017-09-19

Version:

1

Bibliographic Citation:

Zheng, Jie, 2017, "SynLethDB: synthetic lethality database towards discovery of selective and sensitive anticancer drug targets", https://doi.org/10.21979/N9/CVEVDZ, DR-NTU (Data), V1

Study Description

Citation

Title:

SynLethDB: synthetic lethality database towards discovery of selective and sensitive anticancer drug targets

Identification Number:

doi:10.21979/N9/CVEVDZ

Authoring Entity:

Zheng, Jie (Nanyang Technological University)

Software used in Production:

(To be provided)

Grant Number:

AcRF Tier 2 ARC 39/13 (MOE2013-T2-1-079)

Distributor:

DR-NTU (Data)

Access Authority:

Zheng, Jie

Depositor:

Cheng, Wei Yeow

Date of Deposit:

2017-08-26

Holdings Information:

https://doi.org/10.21979/N9/CVEVDZ

Study Scope

Keywords:

Computer and Information Science, Computer and Information Science, Synthetic lethality, Anticancer drug

Abstract:

<p>This dataset is used in the SynLethDB which is the first comprehensive database that harbours a large set of synthetic lethality (SL) gene pairs collected from a variety of sources including biochemical assays, other related databases, computational predictions and text mining. In total, SynLethDB contains 34,085 synthetic lethality pairs and 3,314 publications. Current version covers human and 4 model species, i.e. mouse, fruit fly, worm and yeast. </p>

Kind of Data:

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Methodology and Processing

Sources Statement

Data Access

Other Study Description Materials

Related Publications

Citation

Identification Number:

10.1093/nar/gkv1108

Bibliographic Citation:

Guo, J., Liu, H., & Zheng, J. (2016). SynLethDB: synthetic lethality database toward discovery of selective and sensitive anticancer drug targets. Nucleic Acids Research, 44(D1), D1011-D1017.

Citation

Identification Number:

10356/88975

Bibliographic Citation:

Guo, J., Liu, H., & Zheng, J. (2016). SynLethDB: synthetic lethality database toward discovery of selective and sensitive anticancer drug targets. Nucleic Acids Research, 44(D1), D1011-D1017.

Other Study-Related Materials

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CCLE_Gene_Expression.txt

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Gene Expression

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Other Study-Related Materials

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DrugBank.txt

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Drug Target

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GDSC_Gene_Expression.txt

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Gene Expression

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text/plain

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KIBA.txt

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Drug Target

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NCI60_Gene_Expression.txt

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Gene Expression

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Other Study-Related Materials

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SDL_Human.txt

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SDL pairs in human

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Other Study-Related Materials

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SL_Fly.txt

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SL pairs in fruitfly

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text/plain

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SL_Human.txt

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SL pairs in human

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text/plain

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SL_Mouse.txt

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SL pairs in mouse

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text/plain

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SL_Worm.txt

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SL pairs in worm

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SL_Yeast.txt

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SL pairs in yeast

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text/plain

Other Study-Related Materials

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STITCH.txt

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Drug Target

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