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Part 1: Document Description
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Citation |
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Title: |
Replication Data for: Discrete subset of monocyte-derived cells among typical conventional type 2 dendritic cells can efficiently cross present |
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Identification Number: |
doi:10.21979/N9/H3VUH9 |
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Distributor: |
DR-NTU (Data) |
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Date of Distribution: |
2017-10-30 |
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Version: |
1 |
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Bibliographic Citation: |
Sheng, Jianpeng, 2017, "Replication Data for: Discrete subset of monocyte-derived cells among typical conventional type 2 dendritic cells can efficiently cross present", https://doi.org/10.21979/N9/H3VUH9, DR-NTU (Data), V1 |
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Citation |
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Title: |
Replication Data for: Discrete subset of monocyte-derived cells among typical conventional type 2 dendritic cells can efficiently cross present |
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Identification Number: |
doi:10.21979/N9/H3VUH9 |
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Authoring Entity: |
Sheng, Jianpeng (Nanyang Technological University) |
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Software used in Production: |
FlowJo |
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Distributor: |
DR-NTU (Data) |
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Access Authority: |
Sheng, Jianpeng |
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Depositor: |
Sheng, Jianpeng |
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Date of Deposit: |
2017-09-21 |
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Holdings Information: |
https://doi.org/10.21979/N9/H3VUH9 |
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Study Scope |
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Keywords: |
Medicine, Health and Life Sciences, Medicine, Health and Life Sciences, dendritic cells, antigen presenting cell, monocyte-derived, cross-priming, ontogeny, tumor microenvironment |
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Abstract: |
Dendritic cells (DCs) and macrophages share close developmental pathways but also functional features and therefore, the boundary between these two cell lineages has become blurred. However, even more refined phenotypic or functional characterization and deeper understanding of DC and macrophage ontogeny, have helped to delineate pre-DC derived conventional DCs (cDCs) including cDC1s and cDC2s from monocyte-derived macrophages. Here we have further refined DC/macrophage cells and report that classically defined cDC2s contain also a discrete population of monocyte-derived cells with functional DC features, such as cross presentation. |
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Kind of Data: |
(To be provided) |
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Notes: |
The manuscript based on this data has been accepted by Cell Reports in September 2017. |
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Methodology and Processing |
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Data Access |
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Other Study Description Materials |
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Related Publications |
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Citation |
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Identification Number: |
10.1016/j.celrep.2017.10.024 |
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Bibliographic Citation: |
Sheng, J., Chen, Q., Soncin, I., Ng, S. L., Karjalainen, K., & Ruedl, C. (2017). A Discrete Subset of Monocyte-Derived Cells among Typical Conventional Type 2 Dendritic Cells Can Efficiently Cross-Present. Cell Reports, 21(5), 1203-1214. |
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Citation |
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Identification Number: |
10356/88625 |
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Bibliographic Citation: |
Sheng, J., Chen, Q., Soncin, I., Ng, S. L., Karjalainen, K., & Ruedl, C. (2017). A Discrete Subset of Monocyte-Derived Cells among Typical Conventional Type 2 Dendritic Cells Can Efficiently Cross-Present. Cell Reports, 21(5), 1203-1214. |
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