Virulence Information for Influenza Virus Infection (VI2VI) in Mice (doi:10.21979/N9/ILQBAB)

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Part 1: Document Description
Part 2: Study Description
Part 3: Data Files Description
Part 4: Variable Description
Part 5: Other Study-Related Materials
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Document Description

Citation

Title:

Virulence Information for Influenza Virus Infection (VI2VI) in Mice

Identification Number:

doi:10.21979/N9/ILQBAB

Distributor:

DR-NTU (Data)

Date of Distribution:

2019-04-15

Version:

2

Bibliographic Citation:

Ivan, Fransiskus Xaverius, 2019, "Virulence Information for Influenza Virus Infection (VI2VI) in Mice", https://doi.org/10.21979/N9/ILQBAB, DR-NTU (Data), V2, UNF:6:tcVfZQlYB60+SEUz7/g4jQ== [fileUNF]

Study Description

Citation

Title:

Virulence Information for Influenza Virus Infection (VI2VI) in Mice

Identification Number:

doi:10.21979/N9/ILQBAB

Authoring Entity:

Ivan, Fransiskus Xaverius (Nanyang Technological University)

Software used in Production:

Python

Grant Number:

Singapore AcRF Tier-2 grant MOE2014-T2-2-023

Grant Number:

RGANS1905

Distributor:

DR-NTU (Data)

Access Authority:

Ivan, Fransiskus Xaverius

Depositor:

Ivan, Fransiskus Xaverius

Date of Deposit:

2019-04-15

Holdings Information:

https://doi.org/10.21979/N9/ILQBAB

Study Scope

Keywords:

Medicine, Health and Life Sciences, Medicine, Health and Life Sciences, influenza A virus, mouse models, virulence, proteins, meta-analysis, rule-based classification, random forest

Abstract:

Datasets for Virulence Information for Influenza Virus Infection (VI2VI) in Mice. Please see VI2VI-creation.docx for further details. The analyses of the datasets was first provided as a bioRxiv preprint (see Related Publication) and it has now been accepted for BMC Supplements during InCoB2019 (https://incob2019.org/).

Kind of Data:

Survey data

Methodology and Processing

Sources Statement

Data Access

Other Study Description Materials

Related Publications

Citation

Identification Number:

10.1186/s12864-019-6295-8

Bibliographic Citation:

Ivan, F. X., & Kwoh, C. K. (2019). Rule-based meta-analysis reveals the major role of PB2 in influencing influenza A virus virulence in mice. BMC genomics, 20(9), 973.

Citation

Identification Number:

10356/146319

Bibliographic Citation:

Ivan, F. X., & Kwoh, C. K. (2019). Rule-based meta-analysis reveals the major role of PB2 in influencing influenza A virus virulence in mice. BMC Genomics, 20, 973-.

File Description--f13439

File: extrapolated-incomplete-genomes.tab

  • Number of cases: 84

  • No. of variables per record: 11

  • Type of File: text/tab-separated-values

Notes:

UNF:6:LJ5Ya18vtvU92erY3iyLfA==

File Description--f13438

File: extrapolated-partial-sequences.tab

  • Number of cases: 145

  • No. of variables per record: 11

  • Type of File: text/tab-separated-values

Notes:

UNF:6:NFU6GUKKhdlCJXRr6BXzDQ==

File Description--f13437

File: genomes-metadata.tab

  • Number of cases: 2087

  • No. of variables per record: 9

  • Type of File: text/tab-separated-values

Notes:

UNF:6:bSUeeZ/3TTCwfuWQ4zMqyg==

File Description--f9198

File: VI2VI-mice-x-virus.tab

  • Number of cases: 114

  • No. of variables per record: 9

  • Type of File: text/tab-separated-values

Notes:

UNF:6:GXjIYZ2XzOP0MGFfufjelA==

File Description--f9201

File: VI2VI-virus.tab

  • Number of cases: 112

  • No. of variables per record: 9

  • Type of File: text/tab-separated-values

Notes:

UNF:6:gqvKgcptk1lEZuvF5Db8ng==

Variable Description

List of Variables:

Variables

A

f13439 Location:

Summary Statistics: Max. NaN; Valid 0.0; Mean NaN; Min. NaN; StDev NaN

Variable Format: numeric

Notes: UNF:6:kTxuLDLZnkuv9iz0IaSUcw==

B

f13439 Location:

Variable Format: character

Notes: UNF:6:5V3xZKb31f7QEyO+uErzBg==

C

f13439 Location:

Variable Format: character

Notes: UNF:6:y5OPZEA9+ulZfYRCXV+Big==

D

f13439 Location:

Variable Format: character

Notes: UNF:6:aeNp/iFwbZCj3xhDWEHbVg==

E

f13439 Location:

Variable Format: character

Notes: UNF:6:C1wP3eqH9i2F4FV53dKLiw==

F

f13439 Location:

Variable Format: character

Notes: UNF:6:naW+2py/L2MxSKGOcvVbnw==

G

f13439 Location:

Variable Format: character

Notes: UNF:6:qDNRcV1+YBivudjvyfe/UA==

H

f13439 Location:

Variable Format: character

Notes: UNF:6:DzASb6byVr+PBmZWDfccXA==

I

f13439 Location:

Variable Format: character

Notes: UNF:6:EmBD9MSD9MgELoXVWEm+Lg==

J

f13439 Location:

Variable Format: character

Notes: UNF:6:ndEvMzt/vA06GFnn7I3isQ==

K

f13439 Location:

Variable Format: character

Notes: UNF:6:x5/CPNTd8N9GdOSd9jRMlg==

A

f13438 Location:

Summary Statistics: Max. NaN; StDev NaN; Valid 0.0; Mean NaN; Min. NaN;

Variable Format: numeric

Notes: UNF:6:YdjZiK42tFYl7RfaByyrRw==

B

f13438 Location:

Variable Format: character

Notes: UNF:6:MCfGZikYIx/Sb8gRbfC89A==

C

f13438 Location:

Variable Format: character

Notes: UNF:6:su5gfB/hgjPjJm6J17bdaw==

D

f13438 Location:

Variable Format: character

Notes: UNF:6:1PP9/JV5roVXUTqlpBl7vQ==

E

f13438 Location:

Variable Format: character

Notes: UNF:6:6x2z+2dQ6zECyjSgmEfG6Q==

F

f13438 Location:

Variable Format: character

Notes: UNF:6:8mzUsVMYJ7Gz5YvAXsmLdQ==

G

f13438 Location:

Variable Format: character

Notes: UNF:6:QJ1629EpZ4X1pSmS8skH8Q==

H

f13438 Location:

Variable Format: character

Notes: UNF:6:1+ojqsQurJH1TllkMFIH8Q==

I

f13438 Location:

Variable Format: character

Notes: UNF:6:QHLE4xgfzJ+n4zKsczfUQQ==

J

f13438 Location:

Variable Format: character

Notes: UNF:6:RnEEmP4KlXjYgilFhKizAw==

K

f13438 Location:

Variable Format: character

Notes: UNF:6:RzBxrTdtetSMvnPXHawA2w==

A

f13437 Location:

Summary Statistics: StDev NaN; Max. NaN; Min. NaN; Valid 0.0; Mean NaN;

Variable Format: numeric

Notes: UNF:6:Cvd22BpAqPRfATpTI3WNAA==

MetadataofIAVnucleotidesequencesbeingcollected

f13437 Location:

Variable Format: character

Notes: UNF:6:7PSqXF/uB3LaYD3wPXftNA==

C

f13437 Location:

Variable Format: character

Notes: UNF:6:LeMBKDxJAgBa1tVr43D34Q==

D

f13437 Location:

Variable Format: character

Notes: UNF:6:EeOUHQeBIN8ffxef7UdFyA==

E

f13437 Location:

Variable Format: character

Notes: UNF:6:uNXTBWL8hgQ+EZ/DtFjeQw==

F

f13437 Location:

Variable Format: character

Notes: UNF:6:eXug+FcmOm5rO3Qfk/oaKw==

G

f13437 Location:

Variable Format: character

Notes: UNF:6:9iVfD/1ZjwqhFwjBD5iUQw==

H

f13437 Location:

Variable Format: character

Notes: UNF:6:raxLVGgmyNGpoKm9N0Fqsg==

I

f13437 Location:

Variable Format: character

Notes: UNF:6:CuuMk99toL8uD/aD3XZ8Dg==

Reference

f9198 Location:

Variable Format: character

Notes: UNF:6:wGji39XTfavOkanZbJSP9Q==

Hoststrain

f9198 Location:

Variable Format: character

Notes: UNF:6:N89wbsd6jq8SQULq83UUCQ==

Influenzastrain

f9198 Location:

Variable Format: character

Notes: UNF:6:HyeunNY0lyTDqHspcEXujA==

LD50pointestimate

f9198 Location:

Summary Statistics: StDev 1.8626775314259927; Max. 7.83; Mean 3.4209459459459457; Min. 0.23; Valid 74.0;

Variable Format: numeric

Notes: UNF:6:RhZCNJgiE171yqOoQ06mww==

LD50lowerbound

f9198 Location:

Summary Statistics: Max. 7.0; Valid 28.0; Min. 1.0; Mean 5.074285714285715; StDev 1.3188081841022319

Variable Format: numeric

Notes: UNF:6:nY1G13BdDrTGIsBGVkiG9w==

LD50upperbound

f9198 Location:

Summary Statistics: Valid 14.0; Min. 1.0; Mean 3.85; Max. 6.0; StDev 1.7037289419659185

Variable Format: numeric

Notes: UNF:6:glppYtgL52HV8giqU80r1A==

Infectionunit

f9198 Location:

Variable Format: character

Notes: UNF:6:o0cbf4I4kv95vdS/8CY1uQ==

Two-classvirulencelevel

f9198 Location:

Variable Format: character

Notes: UNF:6:rsmR8VHSogDYlLbuWg6vDw==

Three-classvirulencelevel

f9198 Location:

Variable Format: character

Notes: UNF:6:GcEEJAJmWZrfBoB+cNyPaQ==

Reference

f9201 Location:

Variable Format: character

Notes: UNF:6:TFXdtx01TVLSEqXVwxaqDQ==

Hoststrain

f9201 Location:

Variable Format: character

Notes: UNF:6:Mr6CmnG/vEi3x5T8PqnZrw==

Influenzastrain

f9201 Location:

Variable Format: character

Notes: UNF:6:OEnprVvaajIBis2vFzrRSA==

LD50pointestimate

f9201 Location:

Summary Statistics: Mean 3.2552830188679245; Valid 53.0; StDev 2.089715295085383; Min. 0.3; Max. 7.5

Variable Format: numeric

Notes: UNF:6:1tceQpzy6J9F/sYjoNC7KQ==

LD50lowerbound

f9201 Location:

Summary Statistics: Valid 32.0; StDev 1.2907705875473843; Max. 7.7; Min. 1.0; Mean 5.36875;

Variable Format: numeric

Notes: UNF:6:trJVv5GxOj3WsRrNiWKb1w==

LD50upperbound

f9201 Location:

Summary Statistics: Min. 1.0; Max. 6.0; Mean 3.6448275862068966; StDev 1.4598400614197806; Valid 29.0

Variable Format: numeric

Notes: UNF:6:/bIE/GpRVsHWs7j/JqbCsg==

Infectionunit

f9201 Location:

Variable Format: character

Notes: UNF:6:6seLY0hx9Sq4rArvEowvHQ==

Two-classvirulencelevel

f9201 Location:

Variable Format: character

Notes: UNF:6:GLobL339GY05ekUIZlBAVg==

Three-classvirulencelevel

f9201 Location:

Variable Format: character

Notes: UNF:6:Oy92u5ICYK4cX3yw+NcbKw==

Other Study-Related Materials

Label:

analysis-scripts.7z

Text:

Analysis scripts (for rule-based and random forest models, visualization, and some statistics). A small sample test data will be provided on request.

Notes:

application/x-7z-compressed

Other Study-Related Materials

Label:

List-of-References-for-influenza-infections.docx

Text:

List of references that provide virulence information of influenza virus infections in mice.

Notes:

application/vnd.openxmlformats-officedocument.wordprocessingml.document

Other Study-Related Materials

Label:

preprocessing-scripts.7z

Text:

Preprocessing scripts. A small sample test data will be provided on request.

Notes:

application/x-7z-compressed

Other Study-Related Materials

Label:

VI2VI-creation.docx

Text:

Description of methods and steps taken for creating VI2VI datasets.

Notes:

application/vnd.openxmlformats-officedocument.wordprocessingml.document

Other Study-Related Materials

Label:

VI2VI-preprocessed.7z

Text:

Initial VI2VI dataset - preprocessed VI2VI-raw datasets (determining the lower or upper bound for MLD50, adding the virulence classes, etc.).

Notes:

application/x-7z-compressed

Other Study-Related Materials

Label:

VI2VI-raw.7z

Text:

Raw infection datasets collected from literature.

Notes:

application/x-7z-compressed